Current Degree in progress: PhD student
Thesis Title: Role of IGF-II receptor in the regulation of APP metabolism and its implications in Alzheimer’s disease pathology
Research Interests: Accumulation of amyloid beta (Aβ) peptide under in vivo conditions may initiate/contribute to the neuronal degeneration and development of Alzheimer’s disease (AD) pathology. One of the major functions of the IGF-II receptor is to transport newly synthesized lysosomal hydrolases from the trans-Golgi network to endosomes, which relates to amyloid precursor protein (APP) processing. My project is to discover the changes and relationship of IGF-II receptors and Aβ/APP processing in the cultured neurons, animal models and postpartum brains of AD patients.
Supervisor: Dr. Satyabrata Kar
Awards: Faculty of Medicine & Dentistry/Alberta Health Services Graduate Student Recruitment Studentships