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Rachel Grills

Current Degree in progress: Ph.D.

Thesis Title
:
Combat-related posttraumatic stress disorder: Structural and functional brain changes, cognitive performance, and treatment outcome.

Research Interests: I am predominantly interested in the neurobiology of anxiety and depressive disorders and how brain changes relate to symptom profiles observed in clinical settings. During my M.Sc., I utilized proton magnetic resonance spectroscopy with spectral editing methods to examine in vivo concentrations of various brain neurochemicals (i.e., GABA, glutamate, myoinositol and N-acetylaspartate) in the medial prefrontal cortex and anterior cingulate cortex of patients with generalized social anxiety disorder with and without comorbid major depression. During my doctoral studies I plan to: 1) determine if volumetric changes in stress-affected brain regions (e.g., the hippocampus, amygdala, and anterior cingulate cortex) are associated with functional brain activation patterns during tasks known to elicit activity of these areas; and 2) assess if neurobiological profiles predict cognitive performance and treatment response, in those with PTSD from military service.

Supervisor: Dr. Nicholas Coupland

Awards:

December 2010           Graduate Citizenship Award
March, 2010                   Department of Psychiatry Travel Award       
June, 2009                     Flor-Henry Lecture Scholarship                     
March, 2009                   Government of Alberta Graduate Student Scholarship
September, 2008          Walter H Johns Graduate Fellowship            
September, 2008          Frederick Banting and Charles Best CGS Master's Award
January, 2008               AHFMR/AMHB Studentship in Mental Health Research

Publications:
  • Grills, R.D. (2011). Brain neurochemicals in generalized social anxiety disorder: a proton magnetic resonance study. Master of Science thesis submitted to the University of Alberta.
  • Grills, R.D. (2006). Theta activity in the right parietal lobe during rapid eye movement sleep facilitates memory for arousing pictures. Undergraduate thesis submitted to Trent University.
  • Grills, R. (2007). Face-specific brain mechanisms: Event-related potential (ERP) evidence suggesting the degree of activation is modulated by experimental features. Journal of Undergraduate Studies at Trent, 1, 69-73.
  • Peglar, D., Marchand, K., Grills, R. & Roberts, K. (2007).  An empirical assessment of the proposed Trent university course faculty evaluation questionnaire. Journal of Undergraduate Studies at Trent, 1, 30-35.